Nursing informatics is the branch of science and practice that integrates nursing, its information and knowledge with communication technologies to promote the health of people, families, and communities. Nursing informatics is the specialty in nursing with multiple information and analytical sciences to identify, define, manage and communicate data information in nursing practice. Nursing informatics can be applied to all areas of nursing practice which includes clinical practice, administration, education, research. Nursing informatics play a critical role in the continuous development and improvement of health care technology. The first generation of nursing information system was designed to speed paperwork and communication. Technologies that have evolved due to healthcare/nursing informatics include information to care for patients safety, need to be able to access medical histories, medication lists, imaging results and patients clinical status needed by nurses. It is not unusual to find patient being treated by several physicians as they share little information that may duplicate the tests and prescribed medications that are not compatible with other medications prescribed by another physician. Nursing informatics specialists facilitate data integration, information and knowledge so they can provide a better support to patients, another healthcare providers, and nurses. They use this information to take decisions effectively to improve patient care outcomes. The application of nursing informatics knowledge is empowering for all healthcare practitioner in achieving patient centered care. Communication is inarguable one of the most important aspect of patient safety. They work as developers of communication, information technologies, chief information officer, researcher, educators, and software engineers. The nurse informaticians help in developing and improving technology such as electronic medical records, and computer providing crucial reducing medical errors, health care costs and patient care delay. Depending on the place of work an informatics nurse have many titles, they are known as nurse informaticians, clinical system analyst, an informatics nurse, a clinical informatics, an informatics nurse specialists. All the specialty names refers to nurse with knowledge and experience using technology and applying this to improve nursing and patient care. Nursing informaticians frequently work in hospitals, consulting firms, health care facilities, universities, and corporations. The demand for registered nurse would be increased by 20% between 2012 to 2022, according to Bureau of labor statistics. Nursing informaticians expand their reach to direct patient care, but still experience rewards to helping people and profession. Since 20 years nurses has been working in the role of nursing informatics. Nursing informatics provide challenges and opportunities to transform healthcare in meaningful ways. History of nursing informatics extends since twenty years only, but the field is advancing rapidly as a scientific discipline and has significant implications for patient care. Opportunities are available to impact healthcare at local, state, national, and global levels. The goal of nursing informatics is to improve the health of populations, families, communities, and individuals by optimizing information management and communication. Nurses are expected to have knowledge about the benefits and limitations of technology for communication, and decision-making and attitudes needed to value to technology, and use informatics to both support and protect clients.